Tirzepatide is a prescription medication approved for chronic weight management in adults with obesity or those who are overweight with a related health condition, such as type 2 diabetes

. Marketed under the brand name Zepbound for weight loss, it has been shown to cause significant weight loss when used with a reduced-calorie diet and increased physical activity. 

How tirzepatide works for weight loss

Tirzepatide is a dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics two natural hormones released by the gut after eating, regulating your appetite and digestion. 

Its mechanism leads to weight loss in the following ways: 

• Reduced appetite and cravings: By acting on receptors in the brain that regulate appetite, tirzepatide signals that you are full, which helps reduce cravings and the overall amount of food you eat.

• Increased feeling of fullness: The medication slows the movement of food from the stomach, helping you feel and stay full for longer after eating.

• Improved metabolic function: It regulates insulin and glucagon production to help control blood sugar levels and improve how your body uses energy.